Full name: |
tRNA guanosine(34) transglycosylase |
Synonym: |
JW0396 |
GI: |
67473024 |
Orf: |
b0406 |
COG: |
COG0343 |
UniProt: |
P0A847 |
Structures: |
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Complex: |
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Enzyme type: |
transglycosylase |
Position of modification - modification: |
t:34 - QtRNA
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Comments:
Reaction preQ0(b):preQ0 do not occur under physiological conditions, because normally all preQ0(b) is converted to preQ1(b) by QueF. Do not exist in S. cerevisiae, exist in other yeast (Tgt, O94460, GI20514973, SPAC1687.19c). Structure in complex with tRNA was solved for Tgt enzyme from Zymomonas mobilis (1Q2R).
Protein sequence:
MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIM
KLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVM
IFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGY
AVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVT
DGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIE
EGKLESFVTDFYQRQGREVPPLNVD
Enzymatic activities:
Publications:
Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
New function of vitamin B12: cobamide-dependent reduction of epoxyqueuosine to queuosine in tRNAs of Escherichia coli and Salmonella typhimurium. |
Frey B, McCloskey J, Kersten W, Kersten H |
J Bacteriol |
[details]
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3129401
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Links: