| Full name: |
Ribosomal RNA small subunit methyltransferase A |
| Synonym: |
At5g66360 |
| GI: |
42573814 |
| Orf: |
AT5G66360 |
| COG: |
COG0030 |
| UniProt: |
Q9FK02 |
| Structures: |
|
|
|
| Complex: |
|
| Enzyme type: |
methyltransferase |
| Position of modification - modification: |
s:1914(1518) - m6,6A
s:1915(1519) - m6,6A
|
Comments:
The nuclear genome of Arabidopsis thaliana encodes three dimethylase/mtTFB-like proteins, one of which is Dim1B. The gene product is imported into mitochondria and catalyzes the formation of two adjacent dimethylated residues (m6,6A, positions 1518 and 1519; E. coli numberings) in the loop of a conserved hairpin near the 3'-end of small subunit rRNA. AdoMet is the methyl group donor.
Protein sequence:
MILRLKDQTLIKINSTRSYLSSLVFRRDSHSQARTKPDHDRRRRGYERDVRIEEKKEHDGLFLCKSKGQHLLTNTRILDSIVRSSDIRPTDTVLEIGPGT
GNLTMKLLEAAQNVVAVELDKRMVEILRKRVSDHGFADKLTIIQKDVLKTDFPHFDLVVANIPYNISSPLVAKLVYGSNTFRSATLLLQKEFSRRLLANP
GDSDFNRLAVNVKLVADVKFVMDVSKREFVPPPKVDSSVIRITPKEIIPDVNVQEWLAFTRTCFGKKNKTLGSMFRQKKKVMELQSLSAGRHGSNVEVMN
QTGGDSDSDVEEDGKDDLLCLDTDASMFKERVIEILRTNGFEEKRPSKLSHRELLHLLSLFNQAGIFFHDITSLQMDLHE
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| Comprehensive phylogenetic analysis of evolutionarily conserved rRNA adenine dimethyltransferase suggests diverse bacterial contributions to the nucleus-encoded plastid proteome. |
Park AK, Kim H, Jin HJ |
Mol Phylogenet Evol |
[details]
|
19017544
|
-
|
| A mitochondrial rRNA dimethyladenosine methyltransferase in Arabidopsis. |
Richter U, Kuhn K, Okada S, Brennicke A, Weihe A, Borner T |
Plant J |
[details]
|
19929881
|
-
|
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