| Full name: |
tRNA (cytidine(56)-2'-O)-methyltransferase |
| Synonym: |
|
| GI: |
14521775 |
| Orf: |
PAB1040 |
| COG: |
COG1303 |
| UniProt: |
Q9UYD1 |
| Structures: |
|
|
|
| Complex: |
|
| Enzyme type: |
methyltransferase |
| Position of modification - modification: |
t:56 - Cm
|
Comments:
Contains SPOUT S-adenosylmethionine (AdoMet)-dependent methyltransferase domain which is also found in bacterial and yeast G18 tRNA 2'-O-methylases (SpoU, Trm3). Cm56 tRNA methylation is present only in archaea. In some species it is provided by a C/D sRNP.
Protein sequence:
MIVVLRLGHRPERDKRVTTHVALTARAFGADGIIIVSEEVDLKVKESVEDVVERWGGPFFVKFEKSWRKV
MKEFDGVKVHLTMYGIHIDDIIDELREKLREGRDFMVIVGAEKVPREVYELADYNVAIGNQPHSEVAALA
VFLDRLLEGKGLRKEFKGAKLKIIPQARGKMVVEVQKDAKQAEASGEGASRKNGQLPS
Enzymatic activities:
| Reaction
| Substrate
| Type
| Position
|
|
C:Cm
|
tRNA (t) |
|
56 |
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| The Cm56 tRNA modification in archaea is catalyzed either by a specific 2'-O-methylase, or a C/D sRNP. |
Renalier MH, Joseph N, Gaspin C, Thebault P, Mougin A |
RNA |
[details]
|
15987815
|
-
|