Reaction details: Reaction type level 1: methylation Reaction type level 2: alkylation Reaction type level 3: group addition Input group: H Output group: *C Introduced group name: methyl Introduced group type: hydrocarbon Site: sugar Atom address: 2′O Modification level: 1 Enzymes that catalyse this reaction: Acronym Full name Organism Nop1 rRNA 2′-O-methyltransferase fibrillarin Saccharomyces cerevisiae RlmM Ribosomal RNA large subunit methyltransferase M Escherichia coli RsmI Ribosomal RNA small subunit methyltransferase I Escherichia coli Trm13 tRNA-2′-O-methyltransferase TRM13 Saccharomyces cerevisiae Trm7 tRNA (cytidine(32)/guanosine(34)-2′-O)-methyltransferase Saccharomyces cerevisiae TrmJ tRNA (cytidine(32)/uridine(32)-2′-O)-methyltransferase Escherichia coli TrmJ tRNA (cytidine(32)-2′-O)-methyltransferase Sulfolobus acidocaldarius TrmL tRNA (cytidine(34)-2′-O)-methyltransferase Escherichia coli aTrm56 tRNA (cytidine(56)-2'-O)-methyltransferase Pyrococcus abyssi

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