Modomics - A Database of RNA Modifications

Full name:	alkB homolog 4, lysine demethylase
Synonym:	FLJ20013
GI:	None
Orf:	None
COG:	None
UniProt:	Q9NXW9
Structures:	\| \|
Complex:	None

Comments:

None

Protein sequence:

MAAAAAETPEVLRECGCKGIRTCLICERQRGSDPPWELPPAKTYRFIYCSDTGWAVGTEESDFEGWAFPFPGVMLIEDFVTREEEAELVRLMDRDPWKLS
QSGRRKQDYGPKVNFRKQKLKTEGFCGLPSFSREVVRRMGLYPGLEGFRPVEQCNLDYCPERGSAIDPHLDDAWLWGERLVSLNLLSPTVLSMCREAPGS
LLLCSAPSAAPEALVDSVIAPSRSVLCQEVEVAIPLPARSLLVLTGAARHQWKHAIHRRHIEARRVCVTFRELSAEFGPGGRQQELGQELLRIALSFQGR
PV

Diseases connected to this enzyme:

Description	Reaction	Disease Name
Demethylated tRNA is more sensitive to angiogenin that mediates the cleavage of tRNAs, so tRNA-derived small RNAs are involved in ALKBH3-induced cancer progression by preventing apoptosis of cancer cells.	A:m1A	Cancer (not specified)