Summary:

NameCancer (not specified) (A:m1A)
DescriptionDemethylated tRNA is more sensitive to angiogenin that mediates the cleavage of tRNAs, so tRNA-derived small RNAs are involved in ALKBH3-induced cancer progression by preventing apoptosis of cancer cells.
Related RNA reactionA:m1A
Found in RNAtRNA
Modified TranscriptNone
Mapping TechnologyCLIP-seq
Quantification techniquesLC–MS/MS

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
ALKBH4 alkB homolog 4, lysine demethylase oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
990 Transfer RNA demethylase ALKBH3 promotes cancer progression via induction oftRNA-derived small RNAs. Chen Z Nucleic Acids Res [details] 30541109 5239036

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