Full name: tRNA (adenosine(37)-N6)-methyltransferase
Synonym: YfiC, TrmN6
GI: 13638617
Orf:
COG: COG4123
UniProt: P31825
Structures: | |
Complex:
Enzyme type: methyltransferase
Position of modification - modification: t:37 - m6A

Comments:

SAM-dependent tRNA (adenine-N(6)-)-methyltransferase; modifies A37 of tRNA1Val(cmo5UAC).

Protein sequence:

MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSV MIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGVECSTPQREQA RYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFS PQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM

Enzymatic activities:

Reaction Substrate Type Position
A:m6A tRNA (t) Val/VAC/prokaryotic cytosol 37

Publications:

Title Authors Journal Details PubMed Id DOI
The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC). Golovina AY, Sergiev PV, Golovin AV, Serebryakova MV, Demina I, Govorun VM, Dontsova OA RNA [details] 19383770 -
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