Modomics - A Database of RNA Modifications

Full name:	tRNA pseudouridine synthase 2
Synonym:
GI:	347595823
Orf:	YGL063W
COG:	COG0101
UniProt:	P53167
Structures:	\| \|
Complex:
Enzyme type:	pseudouridine synthase
Position of modification - modification:	t:27 - Y

Comments:

Specificity unpublished

Protein sequence:

MLLGYCGSGYYGMQYNPPHKTIEGEILTKLFDVGAISEENSLAPKKNSFMAAARTDKGVHAMLNLLSLKITLREDTVAKLNAALPPEIRVWGIQPVNKKF
NARSACDSRWYQYLIPEFILIGPPRSSLLHRNVGGSYREDGSQEVWDTFLEQTRGRFSGDELCRLQDTAQKLSESDPLVQDYVGLLSGTLSGYCLSPSKL
DAFEAAMQEYVGTHNFHNFTTGKLWGDPSAQRHIKKVVVSQASPGWICVRIHGQSFMLHQIRRMVALAVLAARCQLPPNIVRNYFNAGPRKYIPRAPAQG
LLLEGPVFDGYNTKLRNLLYCEIRPDDITLERMCRFRERQICTAIAHEETQRHVFCHFVRQMNRLATPLI

Enzymatic activities:

Reaction	Substrate	Type	Position
U:Y	tRNA (t)	Arg/UCU/mitochondrion	26
U:Y	tRNA (t)	Arg/ACG/mitochondrion	26
U:Y	tRNA (t)	His/GUG/mitochondrion	26
U:Y	tRNA (t)	Ser/UAG/mitochondrion	26
U:Y	tRNA (t)	Thr/UAG/mitochondrion	26
U:Y	tRNA (t)	Tyr/GUA/mitochondrion	26
U:Y	tRNA (t)	Lys/UUU/mitochondrion	27

Publications:

Title	Authors	Journal	Details	PubMed Id	DOI
The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:Psi27/28-synthase.	Behm-Ansmant I, Branlant C, Motorin Y	RNA	[details]	17684231	-