Modomics - A Database of RNA Modifications

Full name:	Probable S-adenosyl-L-methionine-dependent RNA methyltransferase RSM22, mitochondrial
Synonym:
GI:	None
Orf:
COG:
UniProt:	P36056
Structures:	\| \|
Complex:
Enzyme type:	methyltransferase
Position of modification - modification:

Comments:

Monomeric variant of Rsm22 methylates mitochondrial tRNAs in vitro. Physiological RNA substrate not known yet.

Protein sequence:

MMKRCFSILPQNVRFSSKFTSLNLPKLDLADFIDSNKRGINVLPSYRDETASTTQATNSKELRLLSKTLQGQSYRDQLELNPDVSKAINNNIMAVHIPNN
LRRVATNYYKEIQEPNSLHRPCRTKMEVDAHIASIFLQNYGSIFQSLKELQKRVGPDNFKPQRILDVGYGPATGIVALNDILGPNYRPDLKDAVILGNAE
MQERAKIILSRQLNEVVDTVEENVSTEKEQETDRRNKNFQEDEHIGEVMTKKINIMTNLRSSIPASKEYDLIILTHQLLHDGNQFPIQVDENIEHYLNIL
APGGHIVIIERGNPMGFEIIARARQITLRPENFPDEFGKIPRPWSRGVTVRGKKDAELGNISSNYFLKVIAPCPHQRKCPLQVGNPNFYTHKEGKDLKFC
NFQKSIKRPKFSIELKKGKLLATSWDGSQGNASRLKGTGRRNGRDYEILNYSYLIFERSHKDENTLKEIKKLRNENVNGKYDIGSLGDDTQNSWPRIIND
PVKRKGHVMMDLCAPSGELEKWTVSRSFSKQIYHDARKSKKGDLWASAAKTQIKGLGDLNVKKFHKLEKERIKQLKKEERQKARKAMESYNELEDSLQFD
DHQFSNFEVMKKLSTFHGNDFLQHVNRK

Publications:

Title	Authors	Journal	Details	PubMed Id	DOI
Expression and analysis of the SAM-dependent RNA methyltransferase Rsm22 from Saccharomyces cerevisiae.	Jahangir Alam,Farah Tazkera Rahman,Shiv K Sah-Teli,Rajaram Venkatesan,M Kristian Koski,Kaija J Autio,J Kalervo Hiltunen,Alexander J Kastaniotis	Acta Crystallogr D Struct Biol	[details]	34076597	-