Modomics - A Database of RNA Modifications

Full name: Serine/threonine-protein kinase BUD32
Synonym: PRPK, LDB14, YGR262c
GI: 6321701
COG: COG3642
UniProt: P53323
Structures: | |
Complex: EKC/KEOPS
Enzyme type: kinase
Position of modification - modification: t:37 - t6A


This protein is present only in Eukaryota and Archaea, it is absent in Bacteria. It is a RIO-type kinase (PRPK), a p53-related protein kinase in human. At variance with most archaeal Bud32, the S. cerevisiae Bud32 is not fused to SceKae1

Protein sequence:



Title Authors Journal Details PubMed Id DOI
The universal Kae1 protein and the associated Bud32 kinase (PRPK), a mysterious protein couple probably essential for genome maintenance in Archaea and Eukarya. Hecker A, Graille M, Madec E, Gadelle D, Le Cam E, van Tilbergh H, Forterre P Biochem Soc Trans [details] 19143597 -



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