Modomics - A Database of RNA Modifications

Full name: NADPH-dependent 7-cyano-7-deazaguanine reductase
Synonym: ykvM, BSU13750
GI: 81555909
COG: COG0780
UniProt: O31678
Structures: | 4F8B | 4FGC |
Enzyme type: oxidoreductase
Position of modification - modification: t:34 - Q


Protein sequence:


Enzymatic activities:

Reaction Substrate Type Position


Title Authors Journal Details PubMed Id DOI
Crystallization and preliminary X-ray characterization of the nitrile reductase QueF: a queuosine-biosynthesis enzyme. Swairjo MA, Reddy RR, Lee B, Van Lanen SG, Brown S, de Crecy-Lagard V, Iwata-Reuyl D, Schimmel P Acta Crystallogr Sect F Struct Biol Cryst Commun [details] 16511203 -
From cyclohydrolase to oxidoreductase: discovery of nitrile reductase activity in a common fold. Van Lanen SG, Reader JS, Swairjo MA, de Crecy-Lagard V, Lee B, Iwata-Reuyl D Proc Natl Acad Sci U S A [details] 15767583 -
Identification of four genes necessary for biosynthesis of the modified nucleoside queuosine. Reader JS, Metzgar D, Schimmel P, de Crecy-Lagard V J Biol Chem [details] 14660578 -
Mechanistic studies of Bacillus subtilis QueF, the nitrile oxidoreductase involved in queuosine biosynthesis. Lee BW, Van Lanen SG, Iwata-Reuyl D Biochemistry [details] 17929836 -
Structural Basis of Biological Nitrile Reduction. Chikwana VM, Stec B, Lee BW, de Crecy-Lagard V, Iwata-Reuyl D, Swairjo MA J Biol Chem [details] 22787148 -

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