Modomics - A Database of RNA Modifications
RlmCD from Streptococcus pneumoniae - protein summary.
23S rRNA (Uracil-C(5))-methyltransferase RlmCD
Position of modification - modification:
RlmCD encoded by SP_1029 in S. pneumoniae is responsible for C5-methylation of U747 and U1939. Methylation of 23S rRNA by the dual-specific methyltransferase, RlmCD, guides the 23S rRNA efficiently to sequential methylation by the other methyltransferase, RlmAII, rendering S. pneumoniae TEL susceptible.
RlmCD-mediated U747 methylation promotes efficient G748 methylation by methyltransferase RlmAII in 23S rRNA in Streptococcus pneumoniae; interplay between two rRNA methylations responsible for telithr
Shoji T, Takaya A, Sato Y, Kimura S, Suzuki T, Yamamoto T
Nucleic Acids Res
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