Modomics - A Database of RNA Modifications

Full name: tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI
Synonym: pimT-like
GI: 5457862
Orf: PAB0283
COG: COG2519
UniProt: Q9V1J7
Structures: | 3LGA | 3LHD | 3MB5 |
Enzyme type: methyltransferase
Position of modification - modification: t:58 - m1A
t:57 - m1I


Protein sequence:


Enzymatic activities:

Reaction Substrate Type Position
A:m1A tRNA (t)   58
A:m1A tRNA (t) 57


Title Authors Journal Details PubMed Id DOI
A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase. Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L Nucleic Acids Res [details] 14739239 -
Structural comparison of tRNA m(1)A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions. Guelorget A, Barraud P, Tisne C, Golinelli-Pimpaneau B BMC Struct Biol [details] 22168821 -
Dynamics of RNA modification by a multi-site-specific tRNA methyltransferase. Hamdane D, Guelorget A, Guerineau V, Golinelli-Pimpaneau B... Nucleic Acids Res [details] 25217588 -
Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase. Guelorget A, Roovers M, Guerineau V, Barbey C, Li X, Golinelli-Pimpaneau B... Nucleic Acids Res [details] 20483913 -

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