| Full name: |
tRNA synthetase, Lysine--tRNA ligase |
| Synonym: |
|
| GI: |
None |
| Orf: |
|
| COG: |
|
| UniProt: |
P0A8N5 |
| Structures: |
|
5YZX |
|
| Complex: |
|
| Enzyme type: |
ligase |
| Position of modification - modification: |
|
Comments:
Converts ATP to diadenosine tri- and tetraphosphates (Ap(3)A/Ap(4)A) in the presence of L-lysine/Mg(2+)/Zn(2+)
Protein sequence:
MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVA
RDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGLQDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVA
RGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRT
LAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPL
ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPA
MRPQK
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli. |
S Onesti,A D Miller,P Brick |
Structure |
[details]
|
7735833
|
-
|
| Stresses that Raise NpA Levels Induce Protective Nucleoside Tetraphosphate Capping of Bacterial RNA. |
Daniel J Luciano,Rose Levenson-Palmer,Joel G Belasco |
Mol Cell |
[details]
|
31178354
|
-
|
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