| Full name: |
Queuine tRNA-ribosyltransferase catalytic subunit 1 |
| Synonym: |
QTRT1, TGUT |
| GI: |
221218971 |
| Orf: |
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| COG: |
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| UniProt: |
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| Structures: |
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| Complex: |
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| Enzyme type: |
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| Position of modification - modification: |
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Comments:
tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine.
Protein sequence:
MAGAATQASLESAPRIMRLVAECSRSRARAGELWLPHGTVATPVFMPVGTQATMKGITTE
QLDALGCRICLGNTYHLGLRPGPELIQKANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEV
TEEGVRFRSPYDGNETLLSPEKSVQIQNALGSDIIMQLDDVVSSTVTGPRVEEAMYRSIR
WLDRCIAAHQRPDKQNLFAIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQFW
RMVALSTSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSALVPTGNLQ
LRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHLTVHNIAYQLQLMSAV
RTSIVEKRFPDFVRDFMGAMYGDPTLCPTWATDALASVGITLG
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structure. |
Chen YC, Kelly VP, Stachura SV, Garcia GA |
RNS |
[details]
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20354154
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10.1261/rna.1997610
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