Comments:

AdoMet is the methyl group donor.

Protein sequence:

Enzymatic activities:

Reaction	Substrate	Type	Position
G:m7G	tRNA (t)	Ala/UGC/prokaryotic cytosol	46
G:m7G	tRNA (t)	Ala/GGC/prokaryotic cytosol	46
G:m7G	tRNA (t)	Arg/ACG/prokaryotic cytosol	46
G:m7G	tRNA (t)	Arg/CCG/prokaryotic cytosol	46
G:m7G	tRNA (t)	Asn/GUU/prokaryotic cytosol	46
G:m7G	tRNA (t)	Asp/GUC/prokaryotic cytosol	46
G:m7G	tRNA (t)	Gly/GCC/prokaryotic cytosol	46
G:m7G	tRNA (t)	His/GUG/prokaryotic cytosol	46
G:m7G	tRNA (t)	Ile/GAU/prokaryotic cytosol	46
G:m7G	tRNA (t)	Ile/CAU/prokaryotic cytosol	46
G:m7G	tRNA (t)	Lys/SUU/prokaryotic cytosol	46
G:m7G	tRNA (t)	Met/CAU/prokaryotic cytosol	46
G:m7G	tRNA (t)	Phe/GAA/prokaryotic cytosol	46
G:m7G	tRNA (t)	Thr/GGU/prokaryotic cytosol	46
G:m7G	tRNA (t)	Trp/CCA/prokaryotic cytosol	46
G:m7G	tRNA (t)	Val/UAC/prokaryotic cytosol	46
G:m7G	tRNA (t)	Val/GAC/prokaryotic cytosol	46
G:m7G	tRNA (t)		46

Publications:

Title	Authors	Journal	Details	PubMed Id	DOI
The yggH gene of Escherichia coli encodes a tRNA (m7G46) methyltransferase.	De Bie LG, Roovers M, Oudjama Y, Wattiez R, Tricot C, Stalon V, Droogmans L, Bujnicki JM	J Bacteriol	[details]	12730187	-
Sequence-structure-function relationships of a tRNA (m7G46) methyltransferase studied by homology modeling and site-directed mutagenesis.	Purta E, van Vliet F, Tricot C, De Bie LG, Feder M, Skowronek K, Droogmans L, Bujnicki JM	Proteins	[details]	15789416	-

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