Full name: | RNA cap gamma-methyltransferase |
---|---|
Synonym: | 7SK snRNA methylphosphate capping enzyme (MePCE), Bicoid-interacting protein 3 homolog |
GI: | 74758999 |
Orf: | MEPCE |
COG: | COG2264 |
UniProt: | Q7L2J0 |
Structures: | | | |
Complex: | |
Enzyme type: | methyltransferase |
Position of modification - modification: |
n:0 - m7Gpp(pN) |
Reaction | Substrate | Type | Position |
---|---|---|---|
pp(pN):mpp(pN) | snRNA (sn) | 7SK | 0 |
Title | Authors | Journal | Details | ||
---|---|---|---|---|---|
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. | Jeronimo C, Forget D, Bouchard A, Li Q, Chua G, Poitras C, Therien C, Bergeron D, Bourassa S, Greenblatt J, Chabot B, Poirier GG, Hughes TR, Blanchette M, Price DH, Coulombe B | Mol Cell | [details] | 17643375 | - |
A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP. | Xue Y, Yang Z, Chen R, Zhou Q | Nucleic Acids Res | [details] | 19906723 | - |