IscA from Escherichia coli - protein summary.
Iron-binding protein iscA
IscA is a scaffold protein for the [Fe-S] clusters. It binds ferredoxin, iron and [2Fe-2S] clusters, and participates in the biosynthesis of iron-sulfur proteins, including (dimethylallyl)adenosine tRNA methylthiotransferase MiaB. IscA homolog in human is IscA1, however its function is not clear.
Iron-sulfur cluster assembly: characterization of IscA and evidence for a specific and functional complex with ferredoxin.
Ollagnier-de-Choudens S, Mattioli T, Takahashi Y, Fontecave M
J Biol Chem
Formation of thiolated nucleosides present in tRNA from Salmonella enterica serovar Typhimurium occurs in two principally distinct pathways.
Leipuviene R, Qian Q, Bjork GR
SufA/IscA: reactivity studies of a class of scaffold proteins involved in [Fe-S] cluster assembly.
Ollagnier-de-Choudens S, Sanakis Y, Fontecave M...
J Biol Inorg Chem
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