Modomics - A Database of RNA Modifications
Trm4 from Pyrococcus abyssi - protein summary.
Position of modification - modification:
t:49 - m5C
Catalyzes m5C formation at several cytosines within tRNAs, with preference for C49. The specificity of the enzyme is increased by complex formation with protein archease (PAB1946) encoded upstream from the MTase gene (PAB1947).
Archease from Pyrococcus abyssi improves substrate specificity and solubility of a tRNA m5C methyltransferase.
Auxilien S, El Khadali F, Rasmussen A, Douthwaite S, Grosjean H...
J Biol Chem
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