TusE from Escherichia coli - protein summary.
tRNA 2-thiouridine synthesizing protein E
Position of modification - modification:
TusE binds TusBCD complex and stimulates sulfur transfer from TusA to TusD. TusE also interacts with a MnmA-tRNA complex. It is necessary for sulfur transfer from IscS cysteine desulfurase to MnmA protein which participates in mnm5s2U synthesis at tRNA wobble positions.
Mechanistic insights into sulfur relay by multiple sulfur mediators involved in thiouridine biosynthesis at tRNA wobble positions.
Ikeuchi Y, Shigi N, Kato J, Nishimura A, Suzuki T
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