| Full name: |
Fibrillarin-like rRNA/tRNA 2′-O-methyltransferase |
| Synonym: |
aFib, Fibrillarin-like, AF_2087 |
| GI: |
11499669 |
| Orf: |
|
| COG: |
COG1889 |
| UniProt: |
O28192 |
| Structures: |
|
1NT2 |
|
| Complex: |
C/D RNP |
| Enzyme type: |
methyltransferase |
| Position of modification - modification: |
l:many - Xm
s:many - Xm
|
Comments:
Homologue of yeast Nop1 protein and human fibrillarin. A catalytic subunit of C/D RNP complex, which in Archaea is composed of FlpA (fibrillarin), L7Ae and Nop56/58 proteins.
Protein sequence:
MKELMRNVYLLDDTLVTKSKYGSHYGEKVFDGYREWVPWRSKLAAMILKGHRLKLRGDERVLYLGAASGTTVSHLADIVDEGIIYAVEYSAKPFEKLLEL
VRERNNIIPLLFDASKPWKYSGIVEKVDLIYQDIAQKNQIEILKANAEFFLKEKGEVVIMVKARSIDSTAEPEEVFKSVLKEMEGDFKIVKHGSLMPYHR
DHIFIHAYRF
Publications:
| Title |
Authors |
Journal |
Details |
PubMed Id |
DOI |
| Structural and thermodynamic evidence for a stabilizing role of Nop5p in S-adenosyl-L-methionine binding to fibrillarin. |
Aittaleb M, Visone T, Fenley MO, Li H |
J Biol Chem |
[details]
|
15286083
|
-
|
| Structure and function of archaeal box C/D sRNP core proteins. |
Aittaleb M, Rashid R, Chen Q, Palmer JR, Daniels CJ, Li H |
Nat Struct Biol |
[details]
|
12598892
|
-
|
Links:
Copyright © Genesilico - All rights reserved
If you have any advice or suggestions for corrections or improvements, please contact:
Andrea Cappannini - lp.vog.bcmii@ininnappaca