Modomics - A Database of RNA Modifications

ID Card:

Full name: Mitochondrial translation optimization protein 1
Synonym: Ips1
GI: 115502421
Orf: YGL236C
COG: COG0445
UniProt: P53070
Alpha Fold Predicted Structure: AF-P53070-F1
Complex: Mto1/Mss1
Enzyme type: other
Position of modification - modification: t:34 - cmnm5s2U



Protein sequence:

MLRVTTLASSCTSFPLQVLRRRLTISSLTSFQPTTKTQVVVIGAGHAGCEAAAASSRTGAHTTLITPSLTDIGKCSCNPSIGGVGKGILVKEIDALDGLMGKVTDLAGVQFKMLNRSKGPAVWGPRAQIDRELYKKYMQRELSDKKAHPNLSLLQNKVADLILYDPGCGHKVIKGVVLDDGTQVGADQVIITTGTFLSAEIHIGDKRIAAGRIGEQPTYGISNTLQNEVGFQLGRLKTGTPARLAKESIDFSALEVQKGDALPVPMSFLNETVSVEPTKQLDCFGTHTTPQMHDFLRNNLHQSIHIQDTTIKGPRYCPSIEAKILRFPDRSSHKIWLEPEGFNSDVIYPNGISNSMPEDVQLQMMRLIPGMANVEILQPAYGVEYDYVDPRQLKPSLETKLVDGLFLAGQINGTTGYEEAAAQGIIAGINAGLLSRQEREQLVLKRSEAYIGVLIDDLINNGVIEPYRMFTSRSEFRISVRADNADFRLTPIGAQLGIISPVRLSQYSRDKHLYDETIRALQNFKLSSQKWSSLLQANIAPQAENRSAWEIFRFKDMDLHKLYECIPDLPINLLDIPMHVVTKINIQGKYEPYIVKQNQFVKAFQADENMLLPQDYDYRQLPTLSTECKLLLNRVQPLTIGQARRIQGITAAALFELYRVARKPSQPVM

Comments:

Yeast mitochondrial homolog of bacterial MnmG (GidA). Favoprotein. Makes a stable complex with Mss1p. Does not work on cytoplasmic tRNAs. Belongs to the bacterial gidA family but is distinct from bacterial Gid, renamed TrmFO.





Alpha Fold Predicted Structure:




Downloading... [106234/599472]


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Protein sequence:

M L R V T T L A S S C T S F P L Q V L R R R L T I S S L T S F Q P T T K T Q V V V I G A G H A G C E A A A A S S R T G A H T T L I T P S L T D I G K C S C N P S I G G V G K G I L V K E I D A L D G L M G K V T D L A G V Q F K M L N R S K G P A V W G P R A Q I D R E L Y K K Y M Q R E L S D K K A H P N L S L L Q N K V A D L I L Y D P G C G H K V I K G V V L D D G T Q V G A D Q V I I T T G T F L S A E I H I G D K R I A A G R I G E Q P T Y G I S N T L Q N E V G F Q L G R L K T G T P A R L A K E S I D F S A L E V Q K G D A L P V P M S F L N E T V S V E P T K Q L D C F G T H T T P Q M H D F L R N N L H Q S I H I Q D T T I K G P R Y C P S I E A K I L R F P D R S S H K I W L E P E G F N S D V I Y P N G I S N S M P E D V Q L Q M M R L I P G M A N V E I L Q P A Y G V E Y D Y V D P R Q L K P S L E T K L V D G L F L A G Q I N G T T G Y E E A A A Q G I I A G I N A G L L S R Q E R E Q L V L K R S E A Y I G V L I D D L I N N G V I E P Y R M F T S R S E F R I S V R A D N A D F R L T P I G A Q L G I I S P V R L S Q Y S R D K H L Y D E T I R A L Q N F K L S S Q K W S S L L Q A N I A P Q A E N R S A W E I F R F K D M D L H K L Y E C I P D L P I N L L D I P M H V V T K I N I Q G K Y E P Y I V K Q N Q F V K A F Q A D E N M L L P Q D Y D Y R Q L P T L S T E C K L L L N R V Q P L T I G Q A R R I Q G I T A A A L F E L Y R V A R K P S Q P V M
100200300400500600SequenceGHITBSN

Secondary Structure Alphabet

  • G: 3-turn helix (310helix)
  • H: α-helix
  • I: 𝝅-helix (5 - turn helix)
  • T: Hydrogen Bonded Turn
  • B: β-sheet
  • S: Bend
  • C: Coil (residues not present in any of the above conformations)
  • N: Not assigned

Download PDB Structures & DSSP Secondary Structures:

Alpha Fold Pdb Files   AF-P53070-F1.pdb  
Alpha Fold Pdbx/mmCIF Files   AF-P53070-F1.cif  
DSSP Secondary Structures   P53070.dssp  





Publications:

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