Summary:

NameAlzheimer (A:m6A)
DescriptionFTO regulates the phosphorylation of Tau in a mTOR-dependent manner by targeting and reducing the mRNA level of TSC1.
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptTSC1
Mapping Technology
Quantification techniques

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
FTO Alpha-ketoglutarate-dependent dioxygenase FTO Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
965 FTO is involved in Alzheimer's disease by targeting TSC1-mTOR-Tau signaling. Li H Biochem Biophys Res Commun [details] 29501742 S0006-291X(18)30457-1

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