Modomics - A Database of RNA Modifications
Bladder cancer (A:m6A) - disease summary
Bladder cancer (A:m6A)
METTL3 is upregulated in bladder cancer cells and tissues. METTL3 could enhance the recognition of pri-miR221/222, which plays an oncogenic role in bladder cancer, by DGCR8 and the subsequent processing to mature miRNAs in an m6A manner.
Related RNA reaction
Found in RNA
m6A dot blot assay, MeRIP-qPCR
Enzymes connected to this disease:
N6-adenosine-methyltransferase 70 kDa subunit
METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner.
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