Name | Brain arteriovenous malformations (AVMs) (A:m6A) |
Description | WTAP is downregulated in brain AVM lesions compared with normal cerebral vessels. DSP is stabilized via WTAP-m6A-IGF2BPs- dependent manner and participated in the regulation of angiogenesis. |
Related RNA reaction | A:m6A |
Found in RNA | mRNA |
Modified Transcript | DSP |
Mapping Technology | MeRIP-seq |
Quantification techniques |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
WTAP | Pre-mRNA-splicing regulator WTAP | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
977 | Wilms' tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation. | Lin-Jian Wang | J Cell Mol Med | [details] | 32281240 | 10.1111/jcmm.15101 |