NameBrain arteriovenous malformations (AVMs) (A:m6A)
DescriptionWTAP is downregulated in brain AVM lesions compared with normal cerebral vessels. DSP is stabilized via WTAP-m6A-IGF2BPs- dependent manner and participated in the regulation of angiogenesis.
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptDSP
Mapping TechnologyMeRIP-seq
Quantification techniques

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
WTAP Pre-mRNA-splicing regulator WTAP Homo sapiens


ID Title Authors Journal Details PubMed Id DOI
977 Wilms' tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation. Lin-Jian Wang J Cell Mol Med [details] 32281240 10.1111/jcmm.15101

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