|Breast cancer (A:m6A)
|m6A upregulates the levels of HBXIP; increases malignant cell growth and proliferation. METTL3 promoted the expression of HBXIP through m6A modification; high expression of METTL3 is related to increased levels of HBXIP in clinical breast cancer tissues and breast cancer cells; METTL3 increases the levels of expression of HBXIP by affecting m6A modification levels on HBXIP mRNA.METTL3 has increased expression in breast cancer cells and has an essential role in progression.
|Related RNA reaction
|Found in RNA
|MeRIP qRT-PCR; m6A dot blot assay
|N6-adenosine-methyltransferase 70 kDa subunit
|HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancervia inhibiting tumor suppressor let-7g.