Modomics - A Database of RNA Modifications

Summary:

NameIntellectual disability (A:m6A)
DescriptionLoss of function mutation in FTO gene leads to leads to postnatal growth retardation and a significant reduction in adipose tissue and lean body mass
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptBDNF pathway
Mapping Technology
Quantification techniques

Enzymes connected to Intellectual disability:

Acronym Full name Enzyme Role Organism Comment
FTO Alpha-ketoglutarate-dependent dioxygenase FTO Homo sapiens

Publications:

ID Title Authors Journal Details PubMed Id DOI
1056 Inactivation of the Fto gene protects from obesity. Linda Koch,Christian Emmerling,Jeanette Vierkotten,Thomas Peters,Jens C BrĂ¼ning, Nature [details] 19234441 10.1038/nature07848
1057 Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis. Li L, Zang L, Zhang F, Chen J, Shen H, Shu L, Liang F, Feng C, Chen D, Tao H, Xu T, Li Z, Kang Y, Wu H, Tang L, Zhang P, Jin P, Shu Q, Li X Hum Mol Genet [details] 28398475 3111724