Modomics - A Database of RNA Modifications

Summary:

NameIntellectual disability (A:m6A)
DescriptionLoss of function mutation in FTO gene leads to leads to postnatal growth retardation and a significant reduction in adipose tissue and lean body mass
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptBDNF pathway
Mapping Technology
Quantification techniques

Enzymes connected to Intellectual disability:

Acronym Full name Enzyme Role Organism Comment
FTO Alpha-ketoglutarate-dependent dioxygenase FTO Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1056 Inactivation of the Fto gene protects from obesity. Julia Fischer Nature [details] 19234441 10.1038/nature07848
1057 Fat mass and obesity-associated (FTO) protein regulates adult neurogenesis. Li L Hum Mol Genet [details] 28398475 3111724