| Name | Obesity (A:m6A) |
| Description | Association between FTO SNPs and higher obesity risk, but further investigation is warranted to identify the causal genetic variants and potential mechanisms underlying the observed genetic associations |
| Related RNA reaction | A:m6A |
| Modified Transcript | None |
| Mapping Technology | None |
| Quantification techniques | None |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| FTO | Alpha-ketoglutarate-dependent dioxygenase FTO | None | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1056 | Inactivation of the Fto gene protects from obesity. | Linda Koch,Christian Emmerling,Jeanette Vierkotten,Thomas Peters,Jens C Brüning, | Nature | [details] | 19234441 | 10.1038/nature07848 |
| 1097 | Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test. | Kihwa Kang,Cuilin Zhang,Rob M van Dam,Peter Kraft,David Hunter,Chih-Hao Lee, | Diabetes | [details] | 18647953 | 10.2337/db08-0006 |
| 1098 | FTO haplotyping underlines high obesity risk for European populations. | Roman Babenko,Junaid Gamieldien, | BMC Med Genomics | [details] | 30871540 | 10.1186/s12920-019-0491-x |
| 1099 | Genome-wide association scan shows genetic variants in the FTO gene are associatedwith obesity-related traits. | Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR | PLoS Genet | [details] | 17658951 | 07-PLGE-RA-0253 |