Summary:

NameObesity (A:m6A)
DescriptionAssociation between FTO SNPs and higher obesity risk, but further investigation is warranted to identify the causal genetic variants and potential mechanisms underlying the observed genetic associations
Related RNA reactionA:m6A
Modified TranscriptNone
Mapping TechnologyNone
Quantification techniquesNone

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
FTO Alpha-ketoglutarate-dependent dioxygenase FTO None Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1056 Inactivation of the Fto gene protects from obesity. Julia Fischer Nature [details] 19234441 10.1038/nature07848
1097 Fat mass-and obesity-associated (FTO) gene variant is associated with obesity: longitudinal analyses in two cohort studies and functional test. Lu Qi Diabetes [details] 18647953 10.2337/db08-0006
1098 FTO haplotyping underlines high obesity risk for European populations. Vladimir Babenko BMC Med Genomics [details] 30871540 10.1186/s12920-019-0491-x
1099 Genome-wide association scan shows genetic variants in the FTO gene are associatedwith obesity-related traits. Scuteri A PLoS Genet [details] 17658951 07-PLGE-RA-0253

Copyright © Genesilico - All rights reserved
If you have any advice or suggestions for corrections or improvements, please contact: Andrea Cappannini - lp.vog.bcmii@ininnappaca