| Name | Pancreatic cancer (A:m6A) |
| Description | m6A methylation is regulating apoptosis and chemo/radioresistance. Methylation of METTL3 target genes is inducing a decrease in apoptotic responses to GEM and it is also protecting from DNA damage after UVC. |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | MAPK cascades, ubiquitin-dependent process, RNA splicing and regulation of the cellular process |
| Mapping Technology | |
| Quantification techniques |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| METTL3 | N6-adenosine-methyltransferase 70 kDa subunit | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1103 | The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells. | Kosuke Taketo | Int J Oncol | [details] | 29345285 | 10.3892/ijo.2017.4219 |