| Name | Parkinson (A:m6A) |
| Description | The overexpression of FTO reduces m6A levels and increases NMDAR1 expression levels, NMDAR1, which could elevate oxidative stress and Ca2+. High expression of NMDAR1 will damage neurons and cause subsequent apoptotic death |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | NMDAR1 |
| Mapping Technology | |
| Quantification techniques | m6A dot blot assay |
| Acronym | Full name | Enzyme Role | Organism |
|---|---|---|---|
| FTO | Alpha-ketoglutarate-dependent dioxygenase FTO | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1108 | Down-Regulation of m6A mRNA Methylation Is Involved in Dopaminergic Neuronal Death. | Xuechai Chen | ACS Chem Neurosci | [details] | 30835997 | 10.1021/acschemneuro.8b00657 |