| Name | Prostate cancer (A:m6A) |
| Description | YTHDF2 is the direct target of miR-493-3p and it is frequently upregulated in both PCa tissues and cell lines. Instead, miR-493-3p is downregulated. The overexpression of YTHDF2 and inhibition of miR-493-3p reduce m6A levels and increase the proliferation and migration of cancer cells |
| Related RNA reaction | A:m6A |
| Modified Transcript | |
| Mapping Technology | |
| Quantification techniques | m6A dot blot assay |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| YTHDF2 | YTH N6-methyladenosine RNA binding protein 2 | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1111 | Downregulation of N-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N-methyladenosine levels. | Jiangfeng Li | Oncotarget | [details] | 29423080 | 10.18632/oncotarget.23365 |