Summary:

NameProstate cancer (A:m6A)
DescriptionYTHDF2 is the direct target of miR-493-3p and it is frequently upregulated in both PCa tissues and cell lines. Instead, miR-493-3p is downregulated. The overexpression of YTHDF2 and inhibition of miR-493-3p reduce m6A levels and increase the proliferation and migration of cancer cells
Related RNA reactionA:m6A
Modified Transcript
Mapping Technology
Quantification techniquesm6A dot blot assay

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
YTHDF2 YTH N6-methyladenosine RNA binding protein 2 oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1111 Downregulation of N-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N-methyladenosine levels. Jiangfeng Li Oncotarget [details] 29423080 10.18632/oncotarget.23365

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