Name | Renal cell carcinoma (A:m6A) |
Description | m6A methylation (induced by METTL3) protects against RCCs proliferation, migration and invasion functions , and EMT and PI3K-Akt-mTOR pathways may be involved in the potential mechanisms. |
Related RNA reaction | A:m6A |
Found in RNA | mRNA |
Modified Transcript | EMT; PI3K-Akt-mTOR |
Mapping Technology | |
Quantification techniques |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
METTL3 | N6-adenosine-methyltransferase 70 kDa subunit | tumor-suppressor | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1114 | The M6A methyltransferase METTL3: acting as a tumor suppressor in renal cell carcinoma. | Xiao Li | Oncotarget | [details] | 29221190 | 10.18632/oncotarget.21726 |