Summary:

NameRenal cell carcinoma (A:m6A)
Descriptionm6A methylation (induced by METTL3) protects against RCCs proliferation, migration and invasion functions , and EMT and PI3K-Akt-mTOR pathways may be involved in the potential mechanisms.
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptEMT; PI3K-Akt-mTOR
Mapping Technology
Quantification techniques

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
METTL3 N6-adenosine-methyltransferase 70 kDa subunit tumor-suppressor Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1114 The M6A methyltransferase METTL3: acting as a tumor suppressor in renal cell carcinoma. Xiao Li Oncotarget [details] 29221190 10.18632/oncotarget.21726

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