Summary:

NameAlzheimer (A:m6A)
Descriptionm6A methyltransferase METTL3 is elevated and the m6A demethylase FTO is decreased in AD mice. The related pathways and genes predicted the potential roles of the differentially expressed m6A methylation RNA in AD.
Related RNA reactionA:m6A
Modified Transcript
Mapping Technology
Quantification techniquesm6A quantification

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
FTO Alpha-ketoglutarate-dependent dioxygenase FTO Homo sapiens
METTL3 N6-adenosine-methyltransferase 70 kDa subunit Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
968 Abnormality of m6A mRNA Methylation Is Involved in Alzheimer's Disease. Min Han Front Neurosci [details] 32184705 10.3389/fnins.2020.00098

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