| Name | Bladder cancer (A:m6A) |
| Description | METTL3 and CDCP1 are upregulated in bladder cancer patient samples. The increased m6A modification and translation of oncogene CDCP1 in the transformed uroepithelial cells indicates the potential role of METTL3/m6A/CDCP1 axis in bladder cancer oncogenesis. |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | CDCP1 |
| Mapping Technology | MeRIP-seq |
| Quantification techniques |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| METTL3 | N6-adenosine-methyltransferase 70 kDa subunit | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 975 | Dynamic mA mRNA methylation reveals the role of METTL3-mA-CDCP1 signaling axis in chemical carcinogenesis. | Huan Jin,Biao Que,Yinghui Chao,Haiqing Zhang,Xiaoling Ying,Zhongyang Zhou,Zusen Yuan,Jialin Su,Bin Wu,Wenjuan Zhang,Defeng Qi,Demeng Chen,Wang Min,Shuibin Lin, | Oncogene | [details] | 30796352 | 10.1038/s41388-019-0755-0 |