Name | Bladder cancer (A:m6A) |
Description | METTL3 and CDCP1 are upregulated in bladder cancer patient samples. The increased m6A modification and translation of oncogene CDCP1 in the transformed uroepithelial cells indicates the potential role of METTL3/m6A/CDCP1 axis in bladder cancer oncogenesis. |
Related RNA reaction | A:m6A |
Found in RNA | mRNA |
Modified Transcript | CDCP1 |
Mapping Technology | MeRIP-seq |
Quantification techniques |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
METTL3 | N6-adenosine-methyltransferase 70 kDa subunit | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
975 | Dynamic mA mRNA methylation reveals the role of METTL3-mA-CDCP1 signaling axis in chemical carcinogenesis. | Fan Yang | Oncogene | [details] | 30796352 | 10.1038/s41388-019-0755-0 |