Summary:

NameBladder cancer (A:m6A)
DescriptionMETTL3 and CDCP1 are upregulated in bladder cancer patient samples. The increased m6A modification and translation of oncogene CDCP1 in the transformed uroepithelial cells indicates the potential role of METTL3/m6A/CDCP1 axis in bladder cancer oncogenesis.
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptCDCP1
Mapping TechnologyMeRIP-seq
Quantification techniques

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
METTL3 N6-adenosine-methyltransferase 70 kDa subunit oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
975 Dynamic mA mRNA methylation reveals the role of METTL3-mA-CDCP1 signaling axis in chemical carcinogenesis. Fan Yang Oncogene [details] 30796352 10.1038/s41388-019-0755-0

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