| Name | Cervical cancer (A:m6A) |
| Description | FTO is frequently overexpressed in human cervical cancer tissues and highly correlated with cervical cancer progression.Mechanistically, FTO directly interacted with E2F1 and Myc mRNAs and inhibition FTO dramatically impaired the translation of these two important oncogenes, thus suppressed cervical cancer cells’ proliferation and migration. |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | MYC, E2F1 |
| Mapping Technology | |
| Quantification techniques | m6A dot blot assay |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| FTO | Alpha-ketoglutarate-dependent dioxygenase FTO | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 994 | The mA eraser FTO facilitates proliferation and migration of human cervical cancer cells. | Dongling Zou | Cancer Cell Int | [details] | 31827395 | 10.1186/s12935-019-1045-1 |