Modomics - A Database of RNA Modifications

Summary:

NameColorectal cancer (A:m6A)
DescriptionYTHDC2 is upregulated in colorectal cancer and it contributes to colon tumor metastasis by promoting translation of HIF-1α
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptHIF-1α
Mapping Technology
Quantification techniques

Enzymes connected to Colorectal cancer:

Acronym Full name Enzyme Role Organism Comment
YTHDC2 YTH domain containing 2 oncogene Homo sapiens

Publications:

ID Title Authors Journal Details PubMed Id DOI
1005 RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiencyby which HIF-1α mRNA is translated. Tanabe A, Tanikawa K, Tsunetomi M, Takai K, Ikeda H, Konno J, Torigoe T, Maeda H, Kutomi G, Okita K, Mori M, Sahara H Cancer Lett [details] 26996300 S0304-3835(16)30076-3