Name | Colorectal cancer (A:m6A) |
Description | YTHDC2 is upregulated in colorectal cancer and it contributes to colon tumor metastasis by promoting translation of HIF-1α |
Related RNA reaction | A:m6A |
Found in RNA | mRNA |
Modified Transcript | HIF-1α |
Mapping Technology | |
Quantification techniques |
Acronym | Full name | Enzyme Role | Organism | Comment |
---|---|---|---|---|
YTHDC2 | YTH domain containing 2 | oncogene | Homo sapiens |
ID | Title | Authors | Journal | Details | ||
---|---|---|---|---|---|---|
1005 | RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiencyby which HIF-1α mRNA is translated. | Tanabe A, Tanikawa K, Tsunetomi M, Takai K, Ikeda H, Konno J, Torigoe T, Maeda H, Kutomi G, Okita K, Mori M, Sahara H | Cancer Lett | [details] | 26996300 | S0304-3835(16)30076-3 |