Summary:

NameColorectal cancer (A:m6A)
DescriptionYTHDC2 is upregulated in colorectal cancer and it contributes to colon tumor metastasis by promoting translation of HIF-1α
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptHIF-1α
Mapping Technology
Quantification techniques

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
YTHDC2 YTH domain containing 2 oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1005 RNA helicase YTHDC2 promotes cancer metastasis via the enhancement of the efficiencyby which HIF-1α mRNA is translated. Tanabe A Cancer Lett [details] 26996300 S0304-3835(16)30076-3

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