Modomics - A Database of RNA Modifications
Gastric cancer (A:m6A) - disease summary
Gastric cancer (A:m6A)
Decreased m6A methylation level, by METTL14 downregulation or FTO upregulation, promotes the activation of oncogenic signaling pathways, such as Wnt and PI3K‐Akt and supports GC cell proliferation, migration and invasion.
Related RNA reaction
Found in RNA
Wnt and PI3K‐Akt pathways and E-chaderin
Enzymes connected to this disease:
Alpha-ketoglutarate-dependent dioxygenase FTO
Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K-Akt signaling in gastric cancer.
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