Summary:

NameGlioblastoma (A:m6A)
DescriptionDecreased methylation promotes GSCs growth and self-renewal. METTL3 induced methylation protects against GSCs growth and self-renewal
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptADAM19
Mapping TechnologyMeRIP-seq
Quantification techniquesm6A dot blot assay

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
METTL3 N6-adenosine-methyltransferase 70 kDa subunit tumor-suppressor Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1027 m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of GlioblastomaStem Cells. Cui Q Cell Rep [details] 28297667 S2211-1247(17)30274-7

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