| Name | Glioblastoma (A:m6A) |
| Description | m6A methylation protects against GSCs growth and self-renewal. FTO induced demethylation regulates GSCs growth and self-renewal, promotes tumor progression and shortens the lifespan of GSC-grafted animals. |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | ADAM19 |
| Mapping Technology | MeRIP-seq |
| Quantification techniques | m6A dot blot assay |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| FTO | Alpha-ketoglutarate-dependent dioxygenase FTO | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1027 | m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of GlioblastomaStem Cells. | Cui Q, Shi H, Ye P, Li L, Qu Q, Sun G, Sun G, Lu Z, Huang Y, Yang CG, Riggs AD, He C, Shi Y | Cell Rep | [details] | 28297667 | 10.1016/j.celrep.2017.02.059 |