Hepatocellular carcinoma (A:m6A) - disease summary
Hepatocellular carcinoma (A:m6A)
Snail, a key transcription factor of EMT, has an increased m6A methylation in its CDS and 3′UTR regions, through METTL3. m6A in CDS of Snail can trigger its translation elongation via interaction with YTHDF1 and eEF-2.
Related RNA reaction
Found in RNA
MeRIP-qPCR, m6A dot blot assay
Enzymes connected to this disease:
N6-adenosine-methyltransferase 70 kDa subunit
RNA mA methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail.
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