| Name | Hypoxia mediated Pulmonary hypertension (A:m6A) |
| Description | m6A level in circRNAs is decreased in lungs of HPH and in particular, two downregulated m6A circRNAs were identified in HPH: circXpo6 and circTmtc3. Furthermore, m6A level influence the stability of circRNAs, thus affecting circRNA–miRNA–mRNA co-expression network in HPH, resulting in the activation of Wnt and FoxO signaling pathways. |
| Related RNA reaction | A:m6A |
| Found in RNA | circRNA |
| Modified Transcript | circXpo6, circTmtc3 |
| Mapping Technology | |
| Quantification techniques | MeRIP-qPCR, MeRIP-RT-PCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1053 | Transcriptome-wide map of mA circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension. | Guowen Wang,Lingfang Wu,Xiuqing Ma,Kejing Ying, | BMC Genomics | [details] | 31931709 | 10.1186/s12864-020-6462-y |