Modomics - A Database of RNA Modifications

Summary:

NameLeukemia (A:m6A)
DescriptionYTHDF2 is overexpressed in AML
Related RNA reactionA:m6A
Modified Transcript
Mapping TechnologyMeRIP-Seq
Quantification techniques

Enzymes connected to Leukemia:

Acronym Full name Enzyme Role Organism Comment
YTHDF2 YTH N6-methyladenosine RNA binding protein 2 oncogene Homo sapiens

Publications:

ID Title Authors Journal Details PubMed Id DOI
1065 Targeting the RNA m(6)A Reader YTHDF2 Selectively Compromises Cancer Stem Cells inAcute Myeloid Leukemia. Paris J, Morgan M, Campos J, Spencer GJ, Shmakova A, Ivanova I, Mapperley C, Lawson H, Wotherspoon DA, Sepulveda C, Vukovic M, Allen L, Sarapuu A, Tavosanis A, Guitart AV, Villacreces A, Much C, Choe J, Azar A, van de Lagemaat LN, Vernimmen D, Nehme A, Mazurier F, Somervaille TCP, Gregory RI, O'Carroll D, Kranc KR Cell Stem Cell [details] 31031138 S1934-5909(19)30120-1