| Name | Leukemia (A:m6A) |
| Description | FTO promotes AML progression |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | MYC, CEBPA, RARA, and ASB2 |
| Mapping Technology | MeRIP-seq |
| Quantification techniques | "m6A dot blot assay; LC-MS/MS" |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| FTO | Alpha-ketoglutarate-dependent dioxygenase FTO | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1066 | Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. | Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, Ni T, Zhang ZS, Zhang T, Li C, Han L, Zhu Z, Lian F, Wei J, Deng Q, Wang Y, Wunderlich M, Gao Z, Pan G, Zhong D, Zhou H, Zhang N, Gan J, Jiang H, Mulloy JC, Qian Z, Chen J, Yang CG | Cancer Cell | [details] | 30991027 | S1535-6108(19)30151-5 |