Summary:

NameLeukemia (A:m6A)
DescriptionFTO promotes AML progression
Related RNA reactionA:m6A
Found in RNAmRNA
Modified TranscriptMYC, CEBPA, RARA, and ASB2
Mapping TechnologyMeRIP-seq
Quantification techniques"m6A dot blot assay; LC-MS/MS"

Enzymes connected to this disease:

Acronym Full name Enzyme Role Organism
FTO Alpha-ketoglutarate-dependent dioxygenase FTO oncogene Homo sapiens
 

Publications:

ID Title Authors Journal Details PubMed Id DOI
1066 Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Huang Y Cancer Cell [details] 30991027 S1535-6108(19)30151-5

Copyright © Genesilico - All rights reserved
If you have any advice or suggestions for corrections or improvements, please contact: Andrea Cappannini - lp.vog.bcmii@ininnappaca