| Name | Non-small cell lung cancer (A:m6A) |
| Description | Increased m6A methylation level reduces USP7 mRNA expression and reduces both the proliferation rate of lung cancer cells and the capacity of colony formation. The increased USP7 mRNA stability through FTO mediated demethylation explaines FTO oncogenic role for the growth of NSCLC cells |
| Related RNA reaction | A:m6A |
| Found in RNA | mRNA |
| Modified Transcript | USP7 |
| Mapping Technology | |
| Quantification techniques | MeRIP-qPCR |
| Acronym | Full name | Enzyme Role | Organism | Comment |
|---|---|---|---|---|
| FTO | Alpha-ketoglutarate-dependent dioxygenase FTO | oncogene | Homo sapiens |
| ID | Title | Authors | Journal | Details | ||
|---|---|---|---|---|---|---|
| 1091 | The m6A demethylase FTO promotes the growth of lung cancer cells by regulating them6A level of USP7 mRNA. | Li J | Biochem Biophys Res Commun | [details] | 30905413 | S0006-291X(19)30482-6 |